5 Antimicrobial Herbs for Your Medicine Chest

When it comes to battling infections and preventing illness, antimicrobial herbs are your go-to allies. These potent remedies contain compounds that target harmful bacteria, fungi, viruses, and protozoa. In other words, antimicrobial herbs encompass a wide range of actions, including antibacterial, antiviral, antifungal, and antiprotozoal properties. Many herbs are multitaskers, offering more than one benefit—like being both antibacterial and antifungal.

Antimicrobial herbs are essential remedies for common colds, the flu, and mild to moderate infections. Depending on the infection, they can be applied topically, taken internally, or both for maximum benefit. I always keep a supply of these herbs in my apothecary year-round, but I make an even bigger effort to stock up ahead of cold and flu season. Antibacterial and antifungal herbs are best stored as dried herbs for topical use, ready to be used in soaks, compresses, or poultices. While herbalists often turn antimicrobial herbs into infused oils or salves, water-based preparations are more effective for topical use. Oil-based remedies can trap moisture, potentially worsening infections by creating an environment where microbes thrive. If you want to learn more about preparing potent and effective herbal medicines, check out our Online Herbal Medicine Making Course.

It’s typically helpful to combine herbal antimicrobials with herbal immunostimulants, which are used on a short-term basis to boost immunity during the initial stages of an infection, as well as throughout the duration of an infectious illness. Classic immunostimulating herbs include echinacea (Echinacea purpurea), garlic (Allium sativum), and spilanthes (Acmella oleracea). You can read more about when to use immune-stimulating herbs in our article, Herbs for the Immune System.

Antimicrobial herbs are beneficial for colds, flu, and other viral, bacterial, and fungal infections.

It’s important to realize that herbs aren’t always the only support you might need to combat infections. Antibiotics and conventional medical care have their place, especially with young children and serious infections. It might surprise you to hear an herbalist say this, but, in most cases, pharmaceutical antibiotics outperform antibacterial herbs. However, it’s also crucial to use antibiotics appropriately and avoid overusing them due to their negative impact on beneficial flora and the risk of promoting antibiotic-resistant bacteria. Plus, when it comes to viral infections, antibiotics offer no benefit and can still cause harm—making it even more important to reserve them for the right situations. For a list of warning signs that indicate the need for medical care, please visit When To Seek Help.

Please note that this article is introductory in scope and doesn’t fully cover each medicinal. If you plan to forage any of these herbs (with the exception of goldenseal and white sage, which are threatened and should not be gathered from the wild), you’ll need to seek out identification tips. You’ll also need to learn foraging ethics and receive guidance before you harvest any plant from the wild! There are deadly poisonous plants out there, so proper identification is paramount.

See our articles on Foraging and Wildcrafting on the blog for more guidance. This is just the tip of the antimicrobial iceberg—for a longer list of antimicrobials, please visit our article on Herbs for the Immune System.

I would venture that many of you are intimately acquainted with the blooms of this familiar vine and have partaken of her nectar, sipped straight from the flower’s slender golden tube. All you sucklers will be happy to know that the familiar honeysuckle vine is also a potent medicinal with far-reaching applications.

Japanese honeysuckle flowers are powerfully antimicrobial and are one of the world’s most widely used medicinal herbs. Honeysuckle can be used internally as a tea or tincture and externally as a poultice or wash. The floral buds and opened blooms are immune-stimulating and strongly antibacterial and antiviral. I use the flowers internally to address hot, inflamed conditions—head colds, flu, urinary tract infections, laryngitis, mastitis, sinus and ear infections, and lower respiratory infections.

The flowers can be gathered both as buds and as opened blooms, and tinctured fresh in alcohol. Honeysuckle is also an effective tea; I combine it with mint and lemon balm to mask its slight bitterness.

Many species of honeysuckle have been used medicinally throughout North America, Europe, and Asia. However, their traditional use and the part employed (bark, leaves, flowers, etc.) varies among species; the biochemistry of the genus is also variable. For example, some honeysuckles have poisonous berries, and some have leaves and bark that can cause vomiting and diarrhea.

Subsequently, we can’t make broad speculations about the medicinal qualities of the entire genus. We’re only talking about Japanese honeysuckle in this article—don’t extrapolate the information here to all honeysuckle species.

Japanese honeysuckle is native to eastern Asia. It has spread throughout much of the world and can now be found in South America, North America, Oceania, and Europe. In the United States, it is especially prolific in the Southeast, but it can be found in almost every state, including Hawaii. Do not plant Japanese honeysuckle, as it’s seriously invasive. Harvesting it for medicine is one way to slow its spread!

Japanese honeysuckle is a perennial woody vine that twines around its host, reaching up to 30 feet (9 m) in length. It can be found in thickets, pastures, fencerows, roadsides, and the forest’s edge. It is not a shrub, unlike many other honeysuckle species.

The leaves are elliptical to oblong and leathery when mature (they feel thickish); they are opposite. The leaves grow to 1.2–3 inches (3-7.5 cm) long and have ciliate margins (tiny hairs, like cilia, growing from the edge of the leaf). The vine has peeling, brown bark.

To learn more about identifying, harvesting, and using Japanese honeysuckle, check out our Online Herbal Immersion Program and our Online Foraging Course: Edible and Medicinal Wild Herbs.

Here are some resources to help you properly identify Japanese honeysuckle:

• Description of Japanese Honeysuckle via The Nature Conservancy
• The Ohio State Guide to Identifying Japanese Honeysuckle

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Usnea is an important medicinal and antimicrobial herb to have on hand in the medicine cabinet. Winter is a fine time to gather usnea, as heavy winds during storms often knock down branches covered with this versatile medicinal. Lichens are symbiotic organisms, consisting of fungi and algae. Usnea is fairly easy to recognize, with its thin string-like branching pattern. It can be differentiated from similar lichens by pulling one of the “strings” slowly apart and looking for a thin white strand at the core.

Usnea is especially helpful in treating respiratory congestion, as it is drying, anti-inflammatory, and antimicrobial. I primarily use usnea in tincture form, and combine it with immune stimulants, for upper and lower respiratory infections. It is also one of my treasured remedies for urinary tract infections, along with corn silk (Zea mays), uva-ursi (Arctostaphylos uva-ursi), and marshmallow root (Althaea officinalis). Most urinary tract infections can be successfully addressed with this protocol, along with unsweetened cranberry juice. Be sure to look out for warning signs of a kidney infection, such as fever, back pain, and persistent urinary symptoms. Kidney infections are best addressed with antibiotics.

Usnea is more effective as a tincture than as a tea when treating infections since its antimicrobial properties are more alcohol-soluble. I tincture dried usnea with organic grain alcohol at 1:4 95% and fresh usnea at 1:2 95%. I use a glass blender to create an usnea/alcohol slurry.

Illustrious for its culinary uses, garden sage is also a versatile medicinal and antimicrobial herb. Its name heralds from the Latin salvere, “to save,” referring to its famous reputation as a lifesaving remedy. This mint family herb has been used therapeutically for centuries with far-reaching applications, ranging from soothing sore throats to washing wounds.

White sage’s medicinal uses are very similar to those of its cousin, although the former is more antimicrobial and stimulating than its domestic brethren. I find that a steam inhalation of the leaves helps to break up respiratory congestion in both the lungs and the sinuses. Try combining it with thyme (Thymus vulgaris) and bee balm (Monarda spp.) in the steam pot, along with a few drops of eucalyptus essential oil. (Omit the eucalyptus if you don’t have any on hand.)

Sage leaves have traditionally been burned after sickness to purify the home. White sage is a sacred herb to many Native American peoples, and its overharvesting by Westerners has resulted in the demise of wild populations.

Because white sage is becoming increasingly rare in its native habitat due to over-gathering, we suggest learning how to cultivate this precious herb. We have a growing guide (plus recipes!) on the blog. Do not gather or purchase wild-harvested white sage.

I try not to play favorites—even with plants—but I must confess that this group of herbs is among my most cherished botanical sweethearts. Bee balm is a powerful antimicrobial herb for colds and flu (it helps to clear the sinuses, break a fever, and overcome infection). It can be taken internally as a tea or tincture and used as a steam inhalation to treat sinus congestion. It’s also a gentle sleep aid, helping to bring rest during the discomfort of illness.

There are over twenty species in the Monarda genus, all of which are native to North America. Using scientific names with this group is important, as common names are often used interchangeably. The species might be called wild bergamot, bee balm, Oswego tea, or horsemint, depending on where you live and whom you are talking with. The name wild bergamot is especially confusing, as bergamot is also applied to the essential oil from the similarly scented Citrus bergamia. It is the citrus oil, and not Monarda, that is used to flavor Earl Grey tea.

The bergamots are some of the showiest medicinals for the garden, with their tousled tops of crimson and lavender. The flowers are edible, adding a vivid zest to any meal. You can medicinally use any of the bee balm species in the Monarda genus.

Goldenseal’s vivid yellow roots are famous in the Native American pharmacopeia and are among the most purchased herbs in commerce today. Unfortunately, goldenseal is often misused—at the first sign of a cold or flu. At this stage, goldenseal’s drying qualities can actually counteract the beneficial “flushing” efforts of the immune system—think thin mucus and a runny nose..

Goldenseal becomes a helpful antimicrobial herb when the symptoms of a cold or flu move deeper into the body or become more serious, such as when a sinus infection develops or when pneumonia becomes a concern.

You’ll want to reach for the goldenseal specifically when thick yellow-green mucus or discharge is present. You can use it as a gargle or take it internally as a tea or tincture.

Goldenseal can be used topically in powder form, or as a compress or wash to treat skin infections.

Please do not gather goldenseal from the wild or purchase wild roots, as they have been heavily overharvested. Grow your own if you can, or purchase organically cultivated roots. For more information on cultivating goldenseal, take a peek at our Guide to Growing Woodland Medicinals. Goldenseal is also one of the featured herbs in my book, The Healing Garden: Cultivating and Handcrafting Herbal Remedies by Juliet Blankespoor.

HERBS FOR IMMUNE SYSTEM SUPPORT